Professor Nicolas Cherbuin
PhD
Head, Centre for Research on Ageing, Health and Wellbeing
ANU College of Health and Medicine
Areas of expertise
- Mental Health 111714
- Epidemiology 111706
- Geriatrics And Gerontology 110308
- Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) 170101
- Neurosciences 1109
- Developmental Psychology And Ageing 170102
Research interests
Prof Cherbuin's main interests relate to the investigation of genetic, environmental, health, lifestyle, and personality factors which influence brain health and plasticity throughout the lifespan, but particularly in ageing populations, and to study how cerebral structure and changes in structure relate to cognition and degenerative diseases. To research these questions he uses large epidemiological datasets and advanced statistical and neuroimaging techniques. Another research focus is the early screening and identification of individuals at risk of cognitive impairment and dementia as well as the identification of associated risk and protective factors. Nic is involved in several randomised controlled trials aimed at decreasing risk of brain and cognitive ageing, and dementia.
Biography
Prof Cherbuin heads the Centre for Research on Ageing, Health and Wellbeing (CRAHW) where he leads the NeuroIMaging and Brain Lab (NIMBL). He was awarded a PhD in 2006 at ANU. His doctoral thesis focused on factors affecting hemispheric interactions. From 2006 until 2008 he was the recipient of an Alzheimer's Australia Research Fellowship. In 2007, he was awarded a NHMRC Training Fellowship to investigate associations between pre-frontal function and structure and cognition and in 2012 he was awarded an ARC Future Fellowship to investigate theoretical models of age- and disease-related changes in brain structure and cognition.
Nic is a chief investigator on the 2015 NHMRC Centre for Excellence in Cognitive Health and a senior chief investigator on a large NHMRC-funded longitudinal study of ageing and mental health, the PATH Through Life study, based at ANU.
Available student projects
A number of potential PhD projects are available to motivated individuals with a background in Psychology, Neuroscience, and other related areas who are interested in investigating associations between cognition, health, laterality and cerebral structure using neuroimaging data
Current student projects
Mark Fraser (PhD candidate) is investigating hippocampal structure in normal ageing using longitudinal data from the PATH project
Hossein Tabatabaei (PhD candidate) researches structural brain changes detectable in the early stages of dementia.
Tianqi Zhang (PhD candidate) is characterising brain differences in type 2 diabetes using shape analysis, and longitudinal methods.
Daniela Oryace (PhD candidate) investigates the associations between the brain behaviour control system (BIS/BAS/FFFS) and their cerebral structural correlates.
Ananthan Ambikarajah (PhD candidate) investigates how body fat is modulated by menopause and how these changes impact cerebral health and cognition.
Khawlah Alateeq (PhD candidate) is evaluating the impact of hypertension and variability in blood pressure on cerebral health.
Sarina Macklin is investigating whether a herbal compound frequently used in Chinese medicine, Rhemannia Glutinosa, is protective for mental and physical health.
Past student projects
Dr Prapti Gautam (PhD 2012). “An investigation into the structural variability of the prefrontal cortex and its relationship to cognition and ageing”
Publications
- Smithson, M, Shou, Y, Dawel, A et al. 2022, 'The Psychological Benefits of an Uncertain World: Hope and Optimism in the Face of Existential Threat', Frontiers in Psychology, vol. 13.
- Alateeq, K, Walsh, E, Abhayaratna, W et al. 2022, 'Effects of Higher Normal Blood Pressure on Brain Are Detectable before Middle-Age and Differ by Sex', Journal of Clinical Medicine, vol. 11, no. 11, pp. 1-16.
- Cherbuin, N, Walsh, E, Leach, L et al. 2022, 'Systemic Inflammation Predicts Alzheimer Pathology in Community Samples without Dementia', Biomedicines, vol. 10, no. 6.
- Zhang, T, Shaw, M & Cherbuin, N 2022, 'Association between Type 2 Diabetes Mellitus and Brain Atrophy: A Meta-Analysis ', Diabetes and Metabolism Journal, vol. 46, no. 5, pp. 781-802.
- Sebastian, P, Cherbuin, N, Barcellos, L et al. 2022, 'Association between Time Spent Outdoors and Risk of Multiple Sclerosis', Neurology, vol. 98, no. 3, pp. E267-E278.
- Calear, A, McCallum, S, Morse, A et al. 2022, 'Psychosocial impacts of home-schooling on parents and caregivers during the COVID-19 pandemic', BMC Public Health, vol. 22, no. 119, pp. 1-8.
- Ambikairajah, A, Walsh, E & Cherbuin, N 2022, 'A review of menopause nomenclature', Reproductive Health, vol. 19, no. 29, pp. 1-15.
- Fraser, M, Walsh, E, Shaw, M et al. 2021, 'Longitudinal effects of physical activity change on hippocampal volumes over up to 12 years in middle and older age community-dwelling individuals', Cerebral Cortex, vol. 2021, no. 00, pp. 1-12.
- Quinlan, C, Rattray, B, Pryor , D et al. 2021, 'A Short-Term Intervention of High-Intensity Exercise and Anodal-tDCS on Motor Learning in Middle-Aged Adults: An RCT', Frontiers in Human Neuroscience, vol. 15, no. 661079, p. 13.
- Darmanthe, N, Tabatabaei Jafari, H & Cherbuin, N 2021, 'Combination of Plasma Neurofilament Light Chain and Mini-Mental State Examination Score Predicts Progression from Mild Cognitive Impairment to Alzheimer's Disease within 5 Years', Journal of Alzheimer's Disease, vol. 82, no. 3, pp. 951-964.
- Espinoza Oyarce, D, Burns, R, Butterworth, P et al. 2021, 'Bridging Classical and Revised Reinforcement Sensitivity Theory Research: A Longitudinal Analysis of a Large Population Study', Frontiers in Psychology, vol. 12, pp. 1-13.
- Cherbuin, N, Walsh, E, Shaw, M et al. 2021, 'Optimal Blood Pressure Keeps Our Brains Younger', Frontiers in Aging Neuroscience, vol. 13, pp. 1-10.
- Alateeq, K, Walsh, E & Cherbuin, N 2021, 'Higher Blood Pressure is Associated with Greater White Matter Lesions and Brain Atrophy: A Systematic Review with Meta-Analysis', Journal of Clinical Medicine, vol. 10, no. 4, pp. 1-19.
- Ambikairajah, A, Tabatabaei Jafari, H, Hornberger, M et al. 2021, 'Age, menstruation history, and the brain', Menopause, vol. 28, no. 2, pp. 167-174.
- McRae, I, Zheng, L, Bourke, S et al. 2021, 'Cost-Effectiveness of Dementia Prevention Interventions', The Journal of Prevention of Alzheimer's Disease, vol. 8, no. 2, pp. 210-217.
- Cherbuin, N, Iijima, K, Kalula, S et al. 2021, 'Societal Need for Interdisciplinary Ageing Research: An International Alliance of Research Universities “Ageing, Longevity and Health� Stream (IARU-ALH) Position Statement', Biomedicine Hub, vol. 6, no. 1, pp. 42-47.
- Batterham, P, Calear, A, McCallum, S et al. 2021, 'Trajectories of depression and anxiety symptoms during the COVID-19 pandemic in a representative Australian adult cohort', Medical Journal of Australia, vol. 214, no. 10, pp. 462-468.
- Murray, C, Aravkin, A, Abbafati, C et al. 2020, 'Five insights from the Global Burden of Disease Study 2019', The Lancet, vol. 396, no. 10258, pp. 1135-1159.
- Fraser, M, Walsh, E, Shaw, M et al. 2020, 'Longitudinal trajectories of hippocampal volume in middle to older age community dwelling individuals', Neurobiology of Aging, vol. 97, pp. 97-105.
- Kurth, F, Cherbuin, N & Luders, E 2020, 'Speaking of aging: Changes in gray matter asymmetry in Broca's area in later adulthood', Cortex, vol. 129, no. -, pp. 133-140.
- Walsh, E, Smith, E, Northey, J et al. 2020, 'Towards an understanding of the physical activity-BDNF-cognition triumvirate: A review of associations and dosage', Ageing Research Reviews, vol. 60, pp. -.
- Walsh, E, Chung, Y, Cherbuin, N et al. 2020, 'Experts' perceptions on the use of visual analytics for complex mental healthcare planning: an exploratory study', BMC Medical Research Methodology, vol. 20, no. 110.
- Burns, R, Andrews, S, Cherbuin, N et al. 2020, 'Role of apolipoprotein E epsilon 4 (APOE*ε4) as an independent risk factor for incident depression over a 12-year period in cognitively intact adults across the lifespan', British Journal of Psychiatry Open, vol. 6, no. 3, pp. 1-7.
- Anstey, K, Cherbuin, N, Kim , S et al. 2020, 'An Internet-Based Intervention Augmented With a Diet and Physical Activity Consultation to Decrease the Risk of Dementia in At-Risk Adults in a Primary Care Setting: Pragmatic Randomized Controlled Trial', Journal of Medical Internet Research, vol. 22, no. 9, pp. 1-15.
- Ambikairajah, A, Tabatabaei Jafari, H, Walsh, E et al. 2020, 'Longitudinal Changes in Fat Mass and the Hippocampus', Obesity, vol. 28, no. 7, pp. 1263-1269.
- McMaster, M, Kim , S, Clare , L et al. 2020, 'Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD)', Journal of American Geriatrics Society, vol. Online , pp. 1-9.
- Walsh, E, Jacka, F, Butterworth, P et al. 2020, 'Midlife susceptibility to the effects of poor diet on diabetes risk', European Journal of Clinical Nutrition, vol. 75, pp. 85-90.
- Makkar, S, Lipnicki, D, Crawford, J et al. 2020, 'Education and the moderating roles of age, sex, ethnicity and apolipoprotein epsilon 4 on the risk of cognitive impairment', Archives of Gerontology and Geriatrics, vol. 91, no. November - December 2020, pp. 1-11.
- Maasakkers, C, Claassen, J, Gardiner, P et al 2020, 'The Association of Sedentary Behaviour and Cognitive Function in People Without Dementia: A Coordinated Analysis Across Five Cohort Studies from COSMIC', Sports Medicine, vol. 50, pp. 403-413.
- Dawel, A, Shou, Y, Smithson, M et al. 2020, 'The Effect of COVID-19 on Mental Health and Wellbeing in a Representative Sample of Australian Adults', Frontiers in Psychiatry, vol. 11, 579985
- Espinoza Oyarce, D, Shaw, M, Alateeq, K ..., Cherbuin, N. 2020, 'Volumetric brain differences in clinical depression in association with anxiety: a systematic review with meta-analysis', Journal of Psychiatry and Neuroscience, vol. 45, no. 6, pp. 406-429.
- Northey, J, Rattray, B, Pumpa , K ..., Cherbuin, N. 2020, 'Objectively measured physical activity is associated with dorsolateral prefrontal cortex volume in older adults', Neuroimage, vol. 221, no. November 2020, pp. 1-8.
- Kurth, F, Cherbuin, N & Luders, E 2019, 'Age but no sex effects on subareas of the amygdala', Human Brain Mapping, vol. 40, no. 6, pp. 1697-1704.
- Hosking, D, Eramudugolla, R, Cherbuin, N et al 2019, 'MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study', Alzheimer's & Dementia, vol. 15, no. 4, pp. 581-589.
- Cherbuin, N, Walsh, E, Baune, B et al 2019, 'Oxidative stress, inflammation and risk of neurodegeneration in a population sample', European Journal of Neurology, vol. 26, no. 11, pp. 1347-1354.
- Walsh, E, Shaw, M, Sachdev, P et al 2019, 'The impact of type 2 diabetes and body mass index on cerebral structure is modulated by brain reserve', European Journal of Neurology, vol. 26, no. 1, pp. 121-127.
- Walsh, E & Cherbuin, N 2019, 'Mapping the literature on nutritional interventions in cognitive health: A data-driven approach', Nutrients, vol. 11, no. 1, pp. 1-9.
- Tabatabaei Jafari, H, Shaw, M, Walsh, E et al. 2019, 'Cognitive/Functional Measures Predict Alzheimer's Disease, Dependent on Hippocampal Volume', Journals of Gerontology Series B: Psychological Sciences and Social Sciences, vol. Online, pp. 1-10pp.
- Ambikairajah, A, Walsh, E, Tabatabaei Jafari, H et al. 2019, 'Fat mass changes during menopause: a metaanalysis', American Journal of Obstetrics and Gynecology, vol. 221, no. 5, pp. 393-409.
- Cherbuin, N & Walsh, E 2019, 'Sugar in mind: Untangling a sweet and sour relationship beyond type 2 diabetes', Frontiers in Neuroendocrinology, vol. 54, no. 2.
- Walsh, E, Shaw, M, Espinoza Oyarce, D et al. 2019, 'Assumption-Free Assessment of Corpus Callosum Shape: Benchmarking and Application', Concepts in Magnetic Resonance Part A, pp. 1-10.
- Northey, J, Rattray, B, Pumpa, K et al 2019, 'Can the intensity of physical activity be accurately measured in older adults using questionnaires?', Journal of Science and Medicine in Sport, vol. 22, no. 7, pp. 803-807.
- Cherbuin, N, Walsh, E & Prina, A 2019, 'Chronic Obstructive Pulmonary Disease and Risk of Dementia and Mortality in Lower to Middle Income Countries', Journal of Alzheimer's Disease, vol. 70, pp. S63-S73.
- Walsh, E, Zhang, T & Cherbuin, N 2019, 'Of fractal and Fourier: A measure for local shape complexity for neurological applications', Journal of Neuroscience Methods, vol. 323, pp. 61-67.
- Tabatabaei Jafari, H, Shaw, M, Walsh, E et al. 2019, 'Regional brain atrophy predicts time to conversion to Alzheimer's disease, dependent on baseline volume', Neurobiology of Aging, vol. 83, pp. 86-94.
- Walsh, E, Shaw, J & Cherbuin, N 2018, 'Trajectories of BMI change impact glucose and insulin metabolism', Nutrition Metabolim and Cardiovascular Diseases, vol. 28, no. 3, pp. 243-251pp.
- Bagheri, N, Wangdi, K, Cherbuin, N et al 2018, 'Combining Geospatial Analysis with Dementia Risk Utilising General Practice Data: A Systematic Review', The Journal of Prevention of Alzheimer's Disease, vol. 5, no. 1, pp. 71-77.
- Walsh, E, Burns, R, Abhayaratna, W et al 2018, 'Physical Activity and Blood Glucose Effects on Weight Gain Over 12 Years in Middle-Aged Adults', Journal of Obesity and Chronic Diseases, vol. 2, no. 1, pp. 20-25.
- Shaw, M, Sachdev, P, Abhayaratna, W et al 2018, 'Body mass index is associated with cortical thinning with different patterns in mid- and late-life', International Journal of Obesity, vol. 42, pp. 455-461.
- Chopra, S, Shaw, M, Shaw, T et al 2018, 'More highly myelinated white matter tracts are associated with faster processing speed in healthy adults', Neuroimage, vol. 171, pp. 332-340pp.
- Zhang, T, Shaw, M, Walsh, E et al 2018, 'Higher fasting plasma glucose is associated with smaller striatal volume and poorer fine motor skills in a longitudinal cohort', Psychiatry Research: Neuroimaging, vol. 278, pp. 1-6pp.
- Tabatabaei Jafari, H, Walsh, E, Shaw, M et al. 2018, 'A simple and clinically relevant combination of neuroimaging and functional indexes for the identification of those at highest risk of Alzheimer's disease', Neurobiology of Aging, vol. 69, pp. 102-110.
- Fraser, M, Shaw, M, Anstey, K et al 2018, 'Longitudinal Assessment of Hippocampal Atrophy in Midlife and Early Old Age: Contrasting Manual Tracing and Semi-automated Segmentation (FreeSurfer)', Brain Topography: Journal of Functional Neurophysiology, vol. 31, pp. 949-962pp.
- Bagheri, N, Wangdi, K, Cherbuin, N et al 2018, 'General Practice Clinical Data Help Identify Dementia Hotspots: A Novel Geospatial Analysis Approach', Journal of Alzheimer's Disease, vol. 61, no. 1, pp. 125-134.
- Bahar-Fuchs, A, Webb, S, Bartsch, L et al 2017, 'Tailored and Adaptive Computerized Cognitive Training in Older Adults at Risk for Dementia: A Randomized Controlled Trial', Journal of Alzheimer's Disease, vol. 60, no. 3, pp. 889-911.
- Cherbuin, N, Anstey, K & Baune, B 2017, 'Oxidative stress, inflammation and mild cognitive impairment', European Psychiatry, vol. 41, pp. 742-742pp.
- Cherbuin, N, Shaw, M, Walsh, E et al 2017, 'Validated Alzheimer's Disease Risk Index (ANU-ADRI) is associated with smaller volumes in the default mode network in the early 60s', Brain Imaging and Behavior, vol. 13, no. 1, pp. 65-74.
- Shaw, M, Abhayaratna, W, Anstey, K et al 2017, 'Increasing Body Mass Index at Midlife is Associated with Increased Cortical Thinning in Alzheimer's Disease-Vulnerable Regions', Journal of Alzheimer's Disease, vol. 59, no. 1, pp. 113-120.
- Walsh, E, Shaw, M, Sachdev, P et al 2017, 'Brain atrophy in ageing: Estimating effects of blood glucose levels vs. other type 2 diabetes effects', Diabetes and Metabolism, vol. -, no. -, pp. 1-4pp.
- Kurth, F, Cherbuin, N & Luders, E 2017, 'Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field', Frontiers in Psychology, vol. 8, no. May, pp. 1-8.
- Kurth, F, Cherbuin, N & Luders, E 2017, 'The impact of aging on subregions of the hippocampal complex in healthy adults', Neuroimage, vol. 163, pp. 296-300pp.
- Irving, M, Eramudugolla, R, Cherbuin, N et al 2017, 'A Critical Review of Grading Systems: Implications for Public Health Policy', Evaluation and the Health Professions, vol. 40, no. 2, pp. 244-262pp.
- Lipnicki, D, Crawford, J, Dutta, R et al 2017, 'Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study', PLoS Medicine, vol. 14, no. 3, pp. e1002261-e1002261.
- Lipnicki, D, Crawford, J, Dutta, R et al 2017, 'Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study', PLoS Medicine, vol. 14, no. 3, pp. e1002261-e1002261.
- Andrews, S, Eramudugolla, R, Velez Valbuena, J et al. 2017, 'Validating the role of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) and a genetic risk score in progression to cognitive impairment in a population-based cohort of older adults followed for 12 years', Alzheimer's Research and Therapy, vol. 9, no. 1, pp. 16-16.
- Northey, J, Cherbuin, N, Pumpa, K et al 2017, 'Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis', British Journal of Sports Medicine, vol. -, no. -, pp. 1-9pp.
- Kim, S, Cherbuin, N & Anstey, K 2017, 'Cancer and cognitive function: The PATH Through Life Project', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 72, no. 9, pp. 1226-1232.
- Tabatabaei Jafari, H, Walsh, E, Shaw, M et al. 2017, 'The cerebellum shrinks faster than normal ageing in Alzheimer's disease but not in mild cognitive impairment', Human Brain Mapping, vol. 38, no. 6, pp. 3141-3150.
- Walsh, E, Jacka, F, Butterworth, P et al 2017, 'The association between Western and Prudent dietary patterns and fasting blood glucose levels in type 2 diabetes and normal glucose metabolism in older Australian adults', Heliyon, vol. 3, no. 6, pp. 1-17pp.
- Walsh, E, Jacka, F, Butterworth, P et al 2017, 'The association between Western and Prudent dietary patterns and fasting blood glucose levels in type 2 diabetes and normal glucose metabolism in older Australian adults', Heliyon, vol. 3, no. 6, pp. 1-17pp.
- Das, D, Cherbuin, N, Anstey, K et al 2017, 'Regional Brain Volumes and ADHD Symptoms in Middle-Aged Adults: The PATH Through Life Study', Journal of Attention Disorders, vol. 21, no. 13, pp. 1073-1086.
- Cherbuin, N, Carey, L, Mortby, M et al 2016, 'Predictors of future stroke in adults 60-64 years living in the community', World Journal of Neurology, vol. 6, no. 1, pp. 14-22pp.
- Zhang, T, Shaw, M, Humphries, J et al 2016, 'Higher fasting plasma glucose is associated with striatal and hippocampal shape differences: The 2sweet project', BMJ Open Diabetes Research & Care, vol. 4, no. 1, pp. 1-8pp.
- O'Donoughue Jenkins, L, Kelly, P, Cherbuin, N et al 2016, 'Evaluating and Using Observational Evidence: The Constrasting Views of Policy Makers and Epidemiologists', Frontiers in Public Health, vol. 4, no. 267, pp. 267-267.
- Kim, S, Cherbuin, N & Anstey, K 2016, 'Assessing reliability of short and tick box forms of the ANU-ADRI: Convenient alternatives of a self-report Alzheimer's disease risk assessment', Alzheimer's & Dementia: Translational Research & Clinical Interventions, vol. 2, no. 2, pp. 93-98.
- Cherbuin, N 2016, 'Dietary Mineral Intake (Magnesium, Calcium, and Potassium) and the Biological Processes of Aging', in Marco Malavolta and Eugenio Mocchegiani (ed.), Molecular Basis of Nutrition and Aging, Academic Press, London, pp. 537-550pp..
- Shaw, M, Abhayaratna, W, Sachdev, P et al 2016, 'Cortical Thinning at Midlife: The PATH Through Life Study', Brain Topography: Journal of Functional Neurophysiology, vol. 29, no. 6, pp. 875-884pp.
- Hemachandra, D, McKetin, R, Cherbuin, N et al 2016, 'Heavy cannabis users at elevated risk of stroke: Evidence from a general population survey', Australian and New Zealand Journal of Public Health, vol. 40, no. 3, pp. 226-230.
- Shaw, M, Sachdev, P, Anstey, K et al 2016, 'Age-related cortical thinning in cognitively healthy individuals in their 60s: The PATH Through Life study', Neurobiology of Aging, vol. 39, pp. 202-209.
- Luders, E, Cherbuin, N & Gaser, C 2016, 'Estimating brain age using high-resolution pattern recognition: Younger brains in long-term meditation practitioners', Neuroimage, vol. 134, pp. 508-513.
- Herath, P, Cherbuin, N, Eramudugolla, R et al 2016, 'The Effect of Diabetes Medication on Cognitive Function: Evidence from the PATH Through Life Study', BioMed Research International, vol. 2016, pp. 7208429-7208429.
- Luders, E & Cherbuin, N 2016, 'Searching for the philosopher's stone: promising links between meditation and brain preservation', Annals of the New York Academy of Sciences, vol. 1373, no. Special Issue, pp. 38-44pp.
- Lueders, E, Kurth, F, Das, D et al. 2016, 'Associations between corpus callosum size and ADHD symptoms in older adults: The PATH through life study', Psychiatry Research: Neuroimaging, vol. 256, pp. 8-14pp.
- McKetin, R, Parasu, P, Cherbuin, N et al 2016, 'A longitudinal examination of the relationship between cannabis use and cognitive function in mid-life adults', Drug and Alcohol Dependence, vol. 169, no. 1, pp. 134-140.
- Andrews, S, Das, D, Cherbuin, N et al 2016, 'Association of genetic risk factors with cognitive decline: the PATH through life project', Neurobiology of Aging, vol. 41, pp. 150-158.
- Cherbuin, N, Sargent, K, Easteal, S et al. 2015, 'Hippocampal atrophy is associated with subjective memory decline: The PATH Through Life study', American Journal of Geriatric Psychiatry, vol. 23, no. 5, pp. 446-455.
- Jacka, F, Cherbuin, N, Anstey, K et al 2015, 'Western diet is associated with a smaller hippocampus: A longitudinal investigation', BMC Medicine, vol. 13, no. 1, pp. 8pp.
- Ayers, B, Luders, E, Cherbuin, N et al 2015, 'Corpus callosum thickness estimation using elastic shape matching', IEEE International Symposium on Biomedical Imaging, ISBI 2015, IEEE Computer Society, TBC, pp. 1518-1521.
- Jacka, F, Cherbuin, N, Anstey, K et al 2015, 'Does reverse causality explain the relationship between diet and depression?', Journal of Affective Disorders, vol. 175, pp. 248-250.
- Cherbuin, N, Sargent, K, Fraser, M et al. 2015, 'Being overweight is associated with hippocampal atrophy: the PATH Through Life Study', International Journal of Obesity, vol. 39, no. 10, pp. 1509 - 1514.
- Luders, E, Cherbuin, N & Kurth, F 2015, 'Forever Young(er): Potential age-defying effects of long-term meditation on gray matter atrophy', Frontiers in Psychology, vol. 5.
- Cherbuin, N, Kim, S & Anstey, K 2015, 'Dementia risk estimates associated with measures of depression: A systematic review and meta-analysis', BMJ Open, vol. 5, no. 12, pp. -.
- Anstey, K, Bahar-Fuchs, A, Herath, P et al 2015, 'Body brain life: A randomized controlled trial of an online dementia risk reduction intervention in middle-aged adults at risk of Alzheimer's disease', Alzheimer's & Dementia: Translational Research & Clinical Interventions, vol. 1, no. 1, pp. 72-80.
- Tabatabaei Jafari, H, Cherbuin, N & Shaw, M 2015, 'CEREBRAL ATROPHY IN MILD COGNITIVE IMPAIRMENT A SYSTEMATIC REVIEW WITH META ANALYSIS', Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 1, no. 4, pp. 487-504.
- Gautam, P, Anstey, K, Wen, W et al 2015, 'Cortical gyrification and its relationships with cortical volume, cortical thickness, and cognitive performance in healthy mid-life adults', Behavioural Brain Research, vol. 287, pp. 331-339.
- Fraser, M, Shaw, M & Cherbuin, N 2015, 'A systematic review and meta-analysis of longitudinal hippocampal atrophy in healthy human ageing', Neuroimage, vol. 112, pp. 364-374.
- Kurth, F, Cherbuin, N & Luders, E 2015, 'Reduced age-related degeneration of the hippocampal subiculum in long-term meditators', Psychiatry Research: Neuroimaging, vol. 232, no. 3, pp. 214-218.
- Barnett, J, Bahar-Fuchs, A, Cherbuin, N et al 2015, 'Interventions to prevent cognitive decline and dementia in adults without cognitive impairment: a systematic review', The Journal of Prevention of Alzheimer's Disease, vol. 2, no. 1, pp. 38-45.
- Cherbuin, N, Mortby, M, Janke, A et al 2015, 'Blood pressure, brain structure, and cognition: Opposite associations in men and women', American Journal of Hypertension, vol. 28, no. 2, pp. 225-231.
- Das, D, Cherbuin, N, Anstey, K et al 2015, 'ADHD Symptoms and Cognitive Abilities in the Midlife Cohort of the PATH Through Life Study', Journal of Attention Disorders, vol. 19, no. 5, pp. 414-424.
- Anstey, K, Sargent, K, Cherbuin, N et al. 2015, 'Self-reported history of chemotherapy and cognitive decline in adults aged 60 and older: The PATH Through Life Project', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 70, no. 6, pp. 729-735.
- Sargent, K, Cherbuin, N, Morris, L et al. 2014, 'The effect of health behavior change on self-rated health across the adult life course: A longitudinal cohort study', Preventive Medicine, vol. 58, pp. 75-80.
- Anstey, K, Sargent, K, Garde, E et al. 2014, 'Cognitive Development Over 8 Years in Midlife and Its Association With Cardiovascular Risk Factors', Neuropsychology, vol. 28, no. 4, pp. 653-665.
- Bunce, D, Bielak, A, Anstey, K et al 2014, 'APOE Genotype and Cognitive Change in Young, Middle-Aged, and Older Adults Living in the Community', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 69, no. 4, pp. 379-386.
- Bunce, D, Bielak, A, Anstey, K et al 2014, 'APOE Genotype and Cognitive Change in Young, Middle-Aged, and Older Adults Living in the Community', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 69, no. 4, pp. 379-386.
- Bielak, A, Cherbuin, N, Anstey, K et al 2014, 'Intraindividual variability is a fundamental phenomenon of aging: Evidence from an 8-year longitudinal study across young, middle, and older adulthood', Developmental Psychology, vol. 50, no. 1, pp. 143-151.
- Cherbuin, N, Nguyen, H, McLachlan, G et al 2014, 'False discovery rate control in magnetic resonance imaging studies via markov random fields', IEEE Transactions on Medical Imaging, vol. 33, no. 8, pp. 1735-1748.
- Das, D, Cherbuin, N, Easteal, S et al 2014, 'Attention deficit/hyperactivity disorder symptoms and cognitive abilities in the late-life cohort of the PATH Through Life Study', PLOS ONE (Public Library of Science), vol. 9, no. 1, pp. e86552-e86552.
- Anstey, K, Cherbuin, N, Herath, P et al 2014, 'A self-report risk index to predict occurrence of dementia in three independent cohorts of older adults: The ANU-ADRI', PLOS ONE (Public Library of Science), vol. 9, no. 1, pp. e86141-e86141.
- Bielak, A, Cherbuin, N, Bunce, D et al 2014, 'Preserved differentiation between physical activity and cognitive performance across young, middle, and older adulthood over 8 years', Journals of Gerontology Series B: Psychological Sciences and Social Sciences, vol. 69, no. 4, pp. 523-532.
- Cherbuin, N, Kumar, R, Sachdev, P et al 2014, 'Dietary mineral intake and risk of Mild Cognitive Impairment: the PATH Through Life project', Frontiers in Aging Neuroscience, vol. 6, no. 4, pp. 1-8.
- Eramudugolla, R, Bielak, A, Bunce, D et al 2014, 'Long-Term Cognitive Correlates of Traumatic Brain Injury across Adulthood and Interactions with APOE Genotype, Sex, and Age Cohorts', Journal of International Neuropsychological Society, vol. 20, no. 4, pp. 444-454.
- Jacka, F, Cherbuin, N, Anstey, K et al 2014, 'Dietary patterns and depressive symptoms over time: examining the relationships with socioeconomic position, health behaviours and cardiovascular risk', PLOS ONE (Public Library of Science), vol. 9, no. 1, pp. e87657-e87657.
- Lamont, A, Mortby, M, Anstey, K et al 2014, 'Using sulcal and gyral measures of brain structure to investigate benefits of an active lifestyle', Neuroimage, vol. 91, pp. 353-359.
- Mortby, M, Burns, R, Janke, A et al 2014, 'Relating education, brain structure, and cognition: The role of cardiovascular disease risk factors', BioMed Research International, vol. Online early version 2014, pp. 271487-271487.
- Das D, Tan X, Bielak AAM et al 2014, 'Cognitive ability, intraindividual variability and common genetic variants of COMT and BDNF: a longitudinal study in a population-based sample of old adults', Psychology and Aging.
- Kim, S, Sargent-Cox, K, Cherbuin, N et al 2014, 'Development of the motivation to change lifestyle and health behaviours for dementia risk reduction scale', Dementia and Geriatric Cognitive Disorders EXTRA, vol. 4, no. 2, pp. 172-183.
- Batterham, P, Bunce, D, Cherbuin, N et al 2013, 'Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength', American Journal of Geriatric Psychiatry, vol. 21, no. 10, pp. 1010-1019.
- Nguyen, H, Janke, A, Cherbuin, N et al 2013, 'Spatial false discovery rate control for magnetic resonance imaging studies', 2013 International Conference on Digital Image Computing: Techniques and Applications, DICTA 2013, Conference Organising Committee, Hobart, TAS.
- Cherbuin, N & Anstey, K 2013, 'Could ignoring higher blood sugar levels in the normal range in nondiabetics compromise cerebral health?', Future Neurology, vol. 8, no. 1, pp. 5-7.
- Gautam, P, Cherbuin, N, Anstey, K et al 2013, 'Sex differences in cortical thickness in middle aged and early old-aged adults: Personality and Total Health Through Life study', Neuroradiology, vol. 55, no. 6, pp. 697-707.
- Mortby, M, Janke, A, Anstey, K et al 2013, 'High "Normal" Blood Glucose Is Associated with Decreased Brain Volume and Cognitive Performance in the 60s: The PATH through Life Study', PLOS ONE (Public Library of Science), vol. 8, no. 9, pp. e73697-e73697.
- Sachdev, P, Lipnicki, D, Kochan, N et al 2013, 'COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups', BMC Neurology, vol. 13, pp. 165-165.
- Bunce, D, Bielak, A, Cherbuin, N et al 2013, 'Utility of Intraindividual Reaction Time Variability to Predict White Matter Hyperintensities: A Potential Assessment Tool for Clinical Contexts?', Journal of International Neuropsychological Society, vol. 19, no. 9, pp. 971-976.
- Cherbuin, N 2013, 'Higher dietary intakes of potassium, calcium and magnesium are associated with a reduced risk of developing vascular dementia', Evidence-Based Mental Health, vol. 16, no. 1, pp. 26-26.
- Batterham, P, Bunce, D, Cherbuin, N et al 2013, 'Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength', American Journal of Geriatric Psychiatry, vol. 21, no. 10, pp. 1010-1019.
- Morris, L, Sargent, K, Cherbuin, N et al. 2013, 'Risk factors for chronic disease in young, midlife and older adults: the PATH Through Life Study', Australian and New Zealand Journal of Public Health, vol. 37, no. 3, pp. 295-296.
- Cherbuin, N & Jorm, A 2013, 'The IQCODE: Using Informant Reports to Assess Cognitive Change in the Clinic and in Older Individuals Living in the Community', in A.J. Larner (ed.), Cognitive Screening Instruments: A practical approach, Springer, London, pp. 165-182.
- Anstey, K, Bahar-Fuchs, A, Herath, P et al 2013, 'A 12-week multidomain intervention versus active control to reduce risk of Alzheimer's disease: Study protocol for a randomized controlled trial', Trials, vol. 14, no. 60, pp. 1-8.
- Cherbuin, N, Luders, E, Chou, Y et al 2013, 'Right, left, and center: How does cerebral asymmetry mix with callosal connectivity?', Human Brain Mapping, vol. 34, no. 7, pp. 1728-1736.
- Anstey, KJ, Cherbuin, N et al 2012, 'Development of a new method for assessing global risk of alzheimer's disease for use in population health approaches to prevention**', Prevention Science, vol. Article in Press.
- Anstey, KJ, Cherbuin, N et al 2012, 'Development of a new method for assessing global risk of alzheimer's disease for use in population health approaches to prevention**', Prevention Science, vol. Article in Press.
- Anstey, KJ, Cherbuin, N, Eramudugolla, R et al 2013, 'Characterizing Mild Cognitive Disorders in the young-old over 8 years: Prevalence, estimated incidence, stability of diagnosis, and impact on IADLs**', Alzheimer's & Dementia.
- Cherbuin, N, Sachdev, P & Anstey, K 2012, 'Higher normal fasting plasma glucose is associated with hippocampal atrophy The PATH Study', Neurology, vol. 79, no. 10, pp. 1019-1026.
- Eramudugolla, R, Cherbuin, N, Easteal, S et al 2012, 'Self-Reported Cognitive Decline on the Informant Questionnaire on Cognitive Decline in the Elderly Is Associated with Dementia, Instrumental Activities of Daily Living and Depression but Not Longitudinal Cognitive Change', Dementia and Geriatric Cognitive Disorders, vol. 34, no. 5-6, pp. 282-291.
- Das, D, Cherbuin, N, Butterworth, P et al 2012, 'A Population-Based Study of Attention Deficit/Hyperactivity Disorder Symptoms and Associated Impairment in Middle-Aged Adults', PLOS ONE (Public Library of Science), vol. 7, no. 2, pp. e31500-e31500.
- Anstey, KJ, Christensen, H, Butterworth, P et al 2011, 'Cohort Profile: The PATH through life project', International Journal of Epidemiology, pp. 1-10.
- Bunce, D, Anstey, KJ, Cherbuin, N et al 2012, 'APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age', Journal of Alzheimer's Disease, vol. Epub ahead of print, no. 30, pp. 1-8.
- Butterworth, P, Cherbuin, N, Anstey, KJ et al 2012, 'The association between financial hardship and amygdala and hippocampal volumes: results from the PATH through life project', Social Cognitive and Affective Neuroscience, vol. Online may 6 2011.
- Cherbuin, N & Anstey, KJ 2012, 'The Mediterranean diet is not related to cognitive change in a large prospective investigation: the PATH Through Life study', American Journal of Geriatric Psychiatry, vol. 00:00, no. 2011, pp. 1-5.
- Das, D, Cherbuin, N, Anstey, KJ, Sachdev, PS & Easteal, S 2011, 'Lifetime cigarette smoking is associated with striatal volume measures', Addiction Biology, vol. Online.
- Young, J, Anstey, KJ & Cherbuin, N 2012, 'Online memory screening �?? are older adults interested and can it work?', Aging and Mental Health, vol. iFirst, pp. 1-7.
- Cherbuin, N, Sachdev, P & Anstey, K 2011, 'Mixed handedness is associated with greater age-related decline in volumes of the hippocampus and amygdala: the PATH through life study', Brain and Behavior, vol. 1, no. 2, pp. 125-134.
- Das, D, Cherbuin, N, Tan, X et al. 2011, 'DRD4-exonIII-VNTR Moderates the Effect of Childhood Adversities on Emotional Resilience in Young-Adults', PLOS ONE (Public Library of Science), vol. 6, no. 5, pp. e20177-e20177.
- Cherbuin, N & Jorm, A 2011, 'The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE)', in M. Abou-Saleh, C. Katona, A. Kumar (ed.), Principles and Practice of Geriatric Psychiatry (3rd ed), John Wiley & Sons Inc, Chichester, UK, pp. 147-151pp.
- Gautam, P, Cherbuin, N, Sachdev, P et al 2011, 'Relationships between cognitive function and frontal grey matter volumes and thickness in middle aged and early old-aged adults: The PATH Through Life Study', Neuroimage, vol. 55, no. 3, pp. 845-855.
- Sargent, K, Cherbuin, N, Sachdev, P et al. 2011, 'Subjective Health and Memory Predictors of Mild Cognitive Disorders and Cognitive Decline in Ageing: The Personality and Total Health (PATH) through Life Study', Dementia and Geriatric Cognitive Disorders, vol. 31, no. 1, pp. 45-52.
- Khan, A, Cherbuin, N, Wen, W et al 2011, 'Optimal weights for local multi-atlas fusion using supervised learning and dynamic information (SuperDyn): Validation on hippocampus segmentation', Neuroimage, vol. 56, no. 1, pp. 126-139.
- Anstey, KJ, Cherbuin, N, Budge, M et al 2011, 'Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies', Obesity Reviews, vol. 12, no. 5, pp. 12 pp.
- Cherbuin, N, Meslin, C, Kumar, R et al 2010, 'Mild cognitive disorders are associated with different patterns of brain asymmetry than normal aging: the PATH through life study', Frontiers in Psychiatry, vol. 1, no. Article 11, pp. 11-11.
- Anstey, KJ & Cherbuin, N, eds, 2010, Is it wine, alcohol in general, or the social context of alcohol drinking that confers health benefits?.
- Bunce, D., Anstey, K.J. Cherbuin, N., Christensen, H., Burns, R.A., Wen, W. Sachdev, P. (2010). Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community. PLoS ONE, 5: 10, e13567.
- Cherbuin, N, Sachdev, P & Anstey, KJ 2010, 'Neuropsychological predictors of transition from healthy cognitive aging to mild cognitive impairment: The PATH through life study', American Journal of Geriatric Psychiatry, vol. 18, no. 8, pp. 723-733.
- Luders, E, Cherbuin, N, Thompson, P et al 2010, 'When more is less: Associations between corpus callosum size and handedness lateralization', Neuroimage, vol. 52, no. 1, pp. 43-49.
- Anstey, K, Mack, H & Cherbuin, N 2009, 'Alcohol Consumption as a Risk Factor for Dementia and Cognitive Decline:A Meta-Analysis of Prospective Studies', American Journal of Geriatric Psychiatry, vol. 17, no. 7, pp. 542-555.
- Cherbuin, N, Anstey, K, Meslin, C et al 2009, 'In Vivo Hippocampal Measurement and Memory: A Comparison of Manual Tracing and Automated Segmentation in a Large Community-Based Sample', PLoS ONE (Public Library of Science), vol. 4, no. 4, pp. e5265.
- Cherbuin, N, Meslin, C, Kumar, R et al. 2009, 'Risk factors of transition from normal cognition to mild cognitive disorder: The PATH trough Life study.', Dementia and Geriatric Cognitive Disorders, vol. 28, no. 1, pp. 47-55.
- Zhou, L, Lieby, P, Barnes, N et al. 2009, 'Hippocampal shape analysis for Alzheimer's disease using an efficient hypothesis test and regularised discriminative deformation', Hippocampus, vol. 19, no. 6, pp. 533-540.
- Anstey, K., Cherbuin, N., & Burns, R. (2009).Medical Conditions and APOE as predictors of subtle cognitive change in mid-life and early-old age: The PATH Through Life Study. Gerontologist, 49: 283-283 Suppl. 2
- Cherbuin, N, Windsor, T, Anstey, K et al 2008, 'Hippocampal volume is positively associated with behavioural inhibition (BIS) in a large community-based sample of mid-life adults: the PATH through life study', Social Cognitive and Affective Neuroscience, vol. 3, no. 3, pp. 262-269.
- Cherbuin, N, Anstey, K & Lipnicki, D 2008, 'Screening for dementia: a review of self assessment instruments', International Psychogeriatrics, vol. 20, no. 3, pp. 431-548.
- Cherbuin, N & Anstey, K 2008, 'DIY dementia screening and online assessment tools', International Psychogeriatrics, vol. 20, no. 3, pp. 641-644.
- Kumar, R, Anstey, K, Cherbuin, N et al 2008, 'Association of Type 2 Diabetes with Depression, Brain Atrophy, and Reduced Fine Motor Speed in a 60 to 64 year old Community Sample', American Journal of Geriatric Psychiatry, vol. 16, no. 12, pp. 989-998.
- Cherbuin, N, Anstey, K, Sachdev, P et al. 2008, 'Total and Regional Gray Matter Volume Is Not Related to APOE*E4 Status in a Community Sample of Middle-Aged Individuals', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 63, no. 5, pp. 501-504.
- Anstey, K. J., Cherbuin, N., Christensen, H., Burns, R., Reglade-Meslin, C., Salim, A., Kumar, R., Jorm, A. F., Sachdev, P. (2008) Follow-up of Mild Cognitive Impairment and Related Disorders Over 4 years in Adults in Their Sixties: The PATH Through Life Study. Dementia and Geriatric Cognitive Disorders. 26:226-233.
- Zhou, L, Hartley, R, Lieby, P et al. 2007, 'A Study of Hippocampal Shape Difference Between Genders by Efficient Hypothesis Test and Discriminative Deformation', MICCAI 2007 - 10th International Conference on Medical Image Computing and Computer Assisted Intervention, ed. Conference Program Committee, Springer, Heidelberg, p. 9.
- Cherbuin, N & Brinkman, J 2007, 'Sensitivity of functional tympanic membrane thermometry (fTMT) as an index of hemispheric activation in cognition.', Laterality, vol. 12, no. 3, pp. 239-261.
- Cherbuin, N, Leach, L, Christensen, H et al 2007, 'Neuroimaging and APOE Genotype: A systemic qualitative review.', Dementia and Geriatric Cognitive Disorders, vol. 24, no. 5, pp. 348-362.
- Cherbuin, N & Brinkman, J 2006, 'Efficiency of callosal transfer and hemispheric interaction', Neuropsychology, vol. 20, no. 2, pp. 178-184.
- Cherbuin, N & Brinkman, J 2006, 'Hemispheric interactions are different in left-handed individuals', Neuropsychology, vol. 20, no. 6, pp. 700-707.
- Cherbuin, N & Brinkman, J 2005, 'Hemispheric activation and interaction: Past activity affects future performance', Laterality, vol. 10, no. 6, pp. 563-579.
- Cherbuin, N & Brinkman, J 2005, 'Practice makes two hemispheres almost perfect', Cognitive Brain Research, vol. 24, pp. 413-422.
- Cherbuin, N & Brinkman, J 2005, 'fTMT, a new measurement method to assess lateralised hemispheric activation using infrared tympanic membrane thermometry', Australiasian experimental psychology conference 2005, ed. Phillip Smith and Charles Liu, Australian Psychological Society, Australia, pp. 48-48.
- Cherbuin, N & Brinkman, J 2004, 'Cognition is cool: Can hemispheric activation be assessed by tympanic membrane thermometry?', Brain and Cognition, vol. 54, pp. 228-231.
Projects and Grants
Grants information is drawn from ARIES. To add or update Projects or Grants information please contact your College Research Office.
- Mental health and the PATH to midlife (Secondary Investigator)
- Centre of Research Excellence in Cognitive Health: Evidence, intervention and population modelling (Secondary Investigator)
- Development and validation of short forms of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) - KT-EDP1 (Secondary Investigator)
- Too sweet for our own good (Primary Investigator)
- Functional and phenotypic effect of dopamine transporter gene variation (Secondary Investigator)
- What is normal brain ageing? An investigation of changes in brain structure and cognition in mid-life (Primary Investigator)
- Improving methods of grading, transferring and facilitating translation of knowledge in population health (Secondary Investigator)
- High risk prescribing in older Australians: prevalence, outcomes and potential for intervention (Primary Investigator)
- Causes and consequences of mental disorders, cognitive decline and dementia over the adult life course and the implications for mental health services: PATH Through Life Wave 4 (Secondary Investigator)
