Areas of expertise
- Cancer Therapy (Excl. Chemotherapy And Radiation Therapy) 111204
- Gene And Molecular Therapy 100401
- Tumour Immunology 110709
- Cellular Immunology 110704
- Immunology 1107
Publications
- Gargett, T, Abbas, M, Rolan, P et al 2018, 'Phase I trial of Lipovaxin-MM, a novel dendritic cell-targeted liposomal vaccine for malignant melanoma', Cancer Immunology, Immunotherapy, vol. 67, pp. 1461-1472pp.
- Carroll, C, Altin, J, Neeman, T et al 2015, 'Repeated fine-needle aspiration of solid tumours in mice allows the identification of multiple infiltrating immune cell types', Journal of Immunological Methods, vol. 425, pp. 102-107.
- Abdus Salam Abul, F & Altin, J 2011, 'Ag-bearing liposomes engrafted with peptides that interact with CD11c/CD18 induce potent Ag-specific and antitumor immunity', International Journal of Cancer, vol. 129, no. 6, pp. 1391-1403.
- Herringson, T & Altin, J 2011, 'Effective tumor targeting and enhanced anti-tumor effect of liposomes engrafted with peptides specific for tumor lymphatics and vasculature', International Journal of Pharmaceutics, vol. 411, no. 1-2, pp. 206-214.
- Abdus Salam Abul, F, Herringson, T, Parish, C et al 2011, 'pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects', Vaccine, vol. 29, no. 40, pp. 6911-6919.
- Herringson, T & Altin, J 2011, 'Increasing the antitumor efficacy of doxorubicin-loaded liposomes with peptides anchored via a chelator lipid', Journal of Drug Targeting, vol. 19, no. 8, pp. 681-689.
- Abdus Salam Abul, F & Altin, J 2010, 'Antigen-containing liposomes engrafted with flagellin-related peptides are effective vaccines that can induce potent antitumor immunity and immunotherapeutic effect', Journal of Immunology, vol. 185, no. 3, pp. 1744-1754.
- Herringson, T & Altin, J 2009, 'Convenient targeting of stealth siRNA-lipoplexes to cells with chelator lipid-anchored molecules', Journal of Controlled Release, vol. 139, pp. 229-238.
- Abdus Salam Abul, F, Bennett, D & Altin, J 2009, 'Liposomal Ag engrafted with peptides of sequence derived from HMGB1 induce potent Ag-specific and anti-tumour immunity', Vaccine, vol. 27, pp. 5846-5854.
- Hamzah, J, Altin, J, Herringson, T et al 2009, 'Targeted Liposomal Delivery of TLR9 Ligands Activates Spontaneous Antitumor Immunity in an Autochthonous Cancer Model', Journal of Immunology, vol. 183, no. 2, pp. 1091-1098.
- Herringson, T, Patlolla, R & Altin, J 2009, 'Targeting of plasmid DNA-lipoplexes to cells with molecules anchored via a metal chelator-lipid', Journal of Gene Medicine, vol. 11, no. 11, pp. 1048-1063.
- Altin, J & Parish, C 2006, 'Liposomal vaccines - targeting the delivery of antigen', Methods, vol. 40, pp. 39-52.
- Altin, J, Banwell, M, Coghlan, P et al. 2006, 'Synthesis of NTA3-DTDA - A Chelator-Lipid that Promotes Stable Binding of His-Tagged Proteins to Membranes', Australian Journal of Chemistry, vol. 59, no. 5, pp. 302-306.
- Altin, J 2005, 'The Human NK cell activation receptor NKp30: Analysis of the expression and cell binding properties of different NKp30 Isoforms', Tissue Antigens, vol. 66, no. 5, p. 584.
- Van Broekhoven, C & Altin, J 2005, 'The Novel Chelator lipid 3(nitrilotriacetic acid)-ditetradecylamine (NTA3-DTDA) promotes stable binding of His-tagged proteins to liposomal membranes: Potent anti-tumor responses induced by simultaneously targeting antigen, cytokine and costimulatory signa', Biochimica et Biophysica Acta: Biomembranes, vol. 1716, pp. 104-116.
- Altin, J & Van Broekhoven, C 2005, 'Improved Targeting of Liposomal membranes with novel chelator lipids: Simultaneous targeting of antigen, cytokine and costimulatory signals to T cells induce potent anti-tumor responses.', Tissue Antigens, vol. 66, no. 5, p. 346.
- Jones, A, Hulett, M, Altin, J et al 2004, 'Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein', Journal of Biological Chemistry, vol. 279, no. 37, pp. 38267-38276.
- Van Broekhoven, C, Parish, C, Demangel, C et al 2004, 'Targeting dendritic cells with antigen-containing liposomes: A highly effective procedure for induction of antitumor immunity and for tumor immunotherapy', Cancer Research, vol. 64, pp. 4357-4365.
- Altin, J, Van Broekhoven, C & Parish, C 2004, 'Targeting dendritic cells with antigen-containing liposomes: antitumour immunity', Expert Opinion on Biological Therapy, vol. 4, no. 11, pp. 1735-1747.
- Parish, C & Altin, J 2003, In vivo targeting of dendritic cells, AU2004266034, Australia.
- Van Broekhoven, C & Altin, J 2002, 'A Novel Approach for Modifying Tumor Cell - Derived Plasma Membrane Vesicles to Contain Encapsulated IL-2 and Engrafted Cosmimulatory Molecules for Use Tumor Immunotherapy', International Journal of Cancer, vol. 98, no. 1, pp. 63-72.
- Van Broekhoven, C & Altin, J 2001, 'A novel system for convenient detection of low-affinity receptor-ligand interactions: Chelator-lipid lipsomes engrafted with recombinant CD4 bind to cells expressing MHC class II', Immunology and Cell Biology, vol. 79, pp. 274-284.
- Altin, J, White, F & Easton, C 2001, 'Synthesis of the chelator lipid nitrilotriacetic acid ditetradecylamine (NTA-DTDA) and its use with the IAsys biosensor to study receptor-ligand interactions on model membranes', Biochimica et Biophysica Acta: Biomembranes, vol. 1513, no. 2, pp. 131-148.
- Van Broekhoven, C, Parish, C, Vassiliou, G et al 2000, 'Engrafting Costimulator Molecules onto Tumor Cell Surfaces with Chelator Lipids: A Potentially Convenient Approach in Cancer Vaccine Development', Journal of Immunology, vol. 164, pp. 2433-2443.
- Gorgani, N, Altin, J & Parish, C 1999, 'Histidine-rich glycoprotein regulates the binding of monomeric IgG and immune complexes by moncytes', International Immunology, vol. 11, no. 8, pp. 1275-1282.
- Gorgani, N, Altin, J & Parish, C 1999, 'Histidine-rich glycoprotein prevents the formation of insoluble immune complexes by rheumatoid factor', Immunology, vol. 98, pp. 456-463.
- Gorgani, N, Parish, C & Altin, J 1999, 'Differential binding of histidine-rich glycoprotein (HRG) to human IgG subclasses and IgG molecules containing kappa and lambda light chains', Journal of Biological Chemistry, vol. 274, pp. 29633-29640.
